The average everyday dose with the barbiturate addict is usually about 1.five grams. As tolerance to barbiturates develops, the quantity necessary to maintain a similar standard of intoxication will increase; tolerance to some lethal dosage, on the other hand, will not increase greater than two-fold. As this occurs, the margin amongst an intoxicati
Although the medical literature abounds with statements which the shorter-acting barbiturates are exceptional for producing sleep whilst the intermediate-acting compounds are more effective in sustaining sleep, controlled research have failed to demonstrate these differential effects. Therefore, as sleep drugs, the barbiturates are of constrained w
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